Beilstein J. Org. Chem.2015,11, 1060–1067, doi:10.3762/bjoc.11.119
: Aubé reaction; biological activity; carbocyclic nucleosides; cyclopentenylatedlactams; cyclopentylated lactams; Introduction
One popular method for the synthesis of N-substituted lactams is the Aubé reaction [1][2][3][4]. Over the last few decades, this reaction has gained popularity and resulted in
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Graphical Abstract
Scheme 1:
The Aubé reaction and its selected applications.